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T-Cell Dependent Antigens

Why is it important to produce cultures that produce just a single antibody? The blood of a human or other vertebrate contains many different kinds of antibodies that will react with a great number of different antigens. Antibodies can be very useful in treating specific diseases that may not respond will to traditional drugs. However unnecessary antibodies could cause damage. Antibodies are an important component of distinguishing self from non-self. If someone has a large number of foreign antibodies injected into them then those antibodies may treat components of the body as antigens. For this reason when antibodies are used they are used in pure clonal form.

View the animation below, then complete the quiz to test your knowledge of the concept.

1Bacterial and viral antigens are presented to helper T-cells by
B)B cells.
C)plasma cells.
D)activated helper T cells.
E)cytotoxic T cells.

2Helper T-cells interact with target cells by recognizing
A)antigens only.
B)MHC proteins only.
C)antigen-MHC protein complexes.
D)either antigens or MHC proteins.
E)neither antigens nor MHC proteins.

3Helper T-cells stimulate
A)cytotoxic T-cells to be become helper T-cells.
B)cytotoxic T-cells to be become B-cells.
C)B cells to become cytotoxic T-cells.
D)B cells to become helper T-cells.
E)B cells to become plasma cells.

4Helper T-cells interact with Class I major histocompatibility complex (MHC) proteins.

5Plasma cells produce antibodies.

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