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Cell Proliferation Signaling Pathway

View the animation below, then complete the quiz to test your knowledge of the concept.






1Growth factor receptors are typically found in the
A)cell membrane.
B)cytoplasm.
C)nucleus.
D)mitochondria.
E)Golgi apparatus.



2It the protein retinoblastoma is ________, it can bind to and ________ the Myc protein.
A)phosphorylated ; activate
B)phosphorylated ; inactivate
C)dephosphorylated ; activate
D)dephosphorylated ; inactivate
E)either B or C



3Which of the following statements about the Myc protein is TRUE?
A)It binds to DNA.
B)It activates the transcription of cyclins and cyclin-dependent kinases.
C)It promotes cell division.
D)A and B
E)A, B and C



4Binding of a growth factor to its receptor, usually sets in motion an intracellular cascade of protein phosphorylations.
A)True
B)False



5The dephosphorylated form of retinoblastoma protein promotes cell division.
A)True
B)False







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