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Antibiotic Inhibition of Protein Synthesis

View the animation below, then complete the quiz to test your knowledge of the concept.

1Which of the following statements about aminoglycosides is TRUE?
A)include streptomycin
B)bind to the 30S ribosomal subunit of the bacterial ribosome
C)cause misreading of the mRNA code
D)A and B
E)A, B and C

2Erythromycin binds to the ______ subunit of bacterial ribosomes thereby inhibiting peptide chain _______.
A)50S; initiation
B)50S; elongation
C)30S; initiation
D)30S; elongation
E)30S; termination

3Which of the following mechanisms can make a bacterium resistant to tetracycline?
A)chemical modification of the drug
B)pumping the drug out of the cell
C)enhancing the binding of the drug to the ribosome
D)A and B
E)A, B and C

4Antibiotics that inhibit bacterial protein synthesis target the 80S ribosomes and therefore do not affect eukaryotes which have 70S ribosomes.

5Tetracyclines inhibit the binding of aminoacyl-tRNAs to the P site of the bacterial ribosome.

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