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Complement Activation

View the animation below, then complete the quiz to test your knowledge of the concept.






1Which of the following statements about complement protein C1 is FALSE?
A)it participates in the classical pathway of complement activation
B)it is composed of three subunits: q, r and s
C)cleaves C2 into C2a and C2b
D)cleaves C3 into C3a and C3b
E)choose this answer if all of the above are TRUE



2Arrange the following in the proper order in which they first appear in the alternative pathway of complement activation.
1. Factor B
2. Factor D
3. C3
A)1, 2, 3
B)2, 1, 3
C)2, 3, 1
D)3, 2, 1
E)3, 1, 2



3Which of the following is a C5 convertase?
A)C4b2b
B)C4a2a
C)C4b3b
D)C4b2b3b
E)C4b2bBb



4The classical pathway of complement activation requires antigen-antibody interactions.
A)True
B)False



5The complex C3bBb is the C3 convertase in the alternative pathway.
A)True
B)False







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