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Diversity of Antibodies

View the animation below, then complete the quiz to test your knowledge of the concept.






1Which of the following processes may generate antibody diversity during B cell development?
A)combinatorial joining that occurs between different nucleotides at the junctions between DNA segments
B)somatic mutations in the variable regions of light chains
C)combinatorial joining that adds different constant regions to the heavy chain
D)A and B
E)A, B and C



2Which of the following represents the correct sequence in combinatorial joining of DNA segments?
A)D and V are first connected together, C joins next, then an mRNA is formed with a specific J segment
B)D and V are first connected together, J joins next, then an mRNA is formed with a specific C segment
C)C and D are first connected together, J joins next, then an mRNA is formed with a specific V segment
D)D and J are first connected together, C joins next, then an mRNA is formed with a specific V segment
E)D and J are first connected together, V joins next, then an mRNA is formed with a specific C segment



3Consider two IgG molecules, each of which reacts with a different epitope. Which of the following statements is FALSE?
A)each molecule consists of two light and two heavy chains
B)they will have the same amino acid sequence in the constant regions of their chains
C)they will have different amino acid sequences in the variable regions of their chains
D)they will bind to two different antigenic determinants
E)choose this answer if all of the above are TRUE



4There are as many genes in the germ line DNA as there are types of antibodies possible.
A)True
B)False



5The same B cell can produce IgG and IgM antibodies.
A)True
B)False







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