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IgE Mediated (Type 1) Hypersensitivity

View the animation below, then complete the quiz to test your knowledge of the concept.

1In IgE mediated hypersensitivity, all of the following are needed except
A)antigen presenting cell
B)B cell
C)IgE antibody
D)mast cell

2IgE molecules attach to
A)mast cells via their variable region
B)mast cells by their constant region
C)T helper cells by their variable region
D)plasma cells by their constant region

3Histamine released by mast cells leads to all of the following symptoms except
A)capillary dilation
B)airway constriction
C)high fever
D)mucus secretion

4For a hypersensitivity response to occur, two bound IgE molecules on a mast cell must react with a specific antigen.

5Activated T helper cells produce cytokines, which stimulate B cells to proliferate and differentiate into plasma cells capable of producing IgE.

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